AUDIOLOGIC AND MR IMAGING CORRELATION IN MENIERE'S DISEASE
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Tfiis is a prospective study to evaluate the utility of high resolution submillimeter MRIfor direct depiction of the endolymphatic duct and sac in healthy subjects and in patients with Meniere's disease. Sixteen pa tients with unilateral Meniere's disease were evaluated by basic audiological evaluation, auditory brainstem response, electronystagmography and MRI. Sixteen age and sex-matched subjects with normal auditory and uestibulnr junction were taken as control Visualization of the endo lymphatic duct and sac was found to be statistically significant less fre quent in Meniere's disease patients (18.8% of the symptomatic ears and 56.2% of the asymptomatic ears) than in the control subjects (90. 6%). The patients with non-visualized duct and sac showed statistically signif icant poorer pure-tone thresholds than the patients with visualized duct and sac. Moreover, there was a statistically significant positive correla tion between the duration of illness and pure-tone average of the sympto matic ears and non-visualization of the endolymphatic duct and sac in the asymptomatic ears of Meniere's disease patients.