Acute effect of sildenafil on myocardial )CrossMa ischemic territories in patientswith stable coronary artery disease
|Full paper||Not Available|
Objectives: To test the safety of sildenafil in patients with stable coronary artery disease (CAD). Methods: Sixty-one patients with stable CAD, documented by coronary angiography were included in this phase I study. Patients were randomized to either single dose sildenafil or matched placebo. Speckle tracking echocardiography was done at baseline and 60min after sildenafil/pla cebo intake to calculate peak systolic strain (PSS) of themost severely affected myocardial segments and the global longitudinal PSS.