HAEMORRHGIC POTENTIAL OF COMBINED DELTIAZEM AND STREPTOKINASE
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Thrombolytic therapy improves outcome in patients with acute myocardial infarction but is still associated with an increased risk of haemorrhagic complication. Calciuin channel blockers are also associated with a comelication of intracerebral haemorrhage . So. the combined use of streptokinase after prolonged use of calcium channel blockers in acute myocardial infarction increased the frequency of these haemorrhagic complication. The present study investigate the effect of combined use of streptokinase after prolonged use of calcium channel blockeralone. streptokinase alone, and combined use of each drug then comparing these with the control group. The result of the present work showed art increase in prothrombirt time and partial thromboplastin time with streptokinase as well as the combined group, but is more prominant in the combined drugs group . Also, there are minimal haemorrhage and organ congestion presented more with the combined group than streptokinase or diltiazem alone.