RELATIONSHIP BETWEEN MICROALBUMINURIA AND SUBCLINICAL CARDIAC STRUCTURAL CHANGES IN ISOLATED SYSTOLIC HYPERTENSION IN ELDERLY PATIENTS
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Isolated systolic hypertension is common in elderly people and accounts for more than 50% of all cases with hypertension above the age of 65 years. Microalburninuria represents an early marker of cardiac structural amage. The aim of this work: is to study the relathionship between micro albuminuria and subdinical cardiac structural changes (septal wall thickness (51417, left ventricular mass (LVM) and left ventricular mass index (LVMI)) in isolated systolic hypertension in elderly patients. Result: showed significant positive correlation between microalburninuria nd cardiac structural changes (LVMI - P = 0.001, SW7' - P = 0.002 and LVM - P = 0.0001).7'here was a significant positive correlation between the duration of hypertension and microalbuminuria, LVM (P=0.02) and LW-I. (P=0.001). Also,there was a significant positive correlation between age of patients and LVM (P = 0.01) and LVH (P = 0.01). Conclusion: Taken together this study showed that microalbumirturia represents an early marker of crdirac structural changes in isolated systolic hypertension in elderly patients It is considered one of the new associated risk factors of hypertension. Cardiovascular prognosis depends not only on the blood pressure level but also on hte presence of target organ dam- age. So we recommend early detection of microalbuminuria in every hypertensive patient as it is art early sign of endothelial dysfunction and damaged blood vessels.