PLASMA FIBRONECTIN LEVEL IN ACUTE MYOCARDIAL INFARCTION
|Full paper||Not Available|
This study was carried out on twenty patients with acute myocardial infarction (10 had anterior and 10 had inferior infarction) in a trial to find wit any relationship between plasma fibronectin level and severity of myocardial infarction. Plasma fibronectin was significantly reduced on the 1st, 2nd, 3rd and 8th postinfarction days and raised by the 201h day. However, Marked diminution was inure noticeable in anterior compared to inferior infarction. Plasma fibronectin positively correlated with the ejection fraction and fractional shortening and negatively correlated with the level of cardiac enzymes, with leucocytosis and ES!? and with the size of infarction. Therefore, the degree of diminution of plasma fibronectin can be considered as a parameter reflecting the severity of myocardial involvement. On the other hand its rise signifies myocardial healing. However, trial for evaluating the therapeutic efficacy of exogenous fibronectin in promoting healing of acute myocardial infarction might be recommended as a future research.