IDENTIFICATION OF HAPTOGLOBIN AS A PREDICTOR OF DIABETIC NEPHROPATHY
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Diabetic nephropathy is characterized by excessive urinary excretion of certain proteins, which is thought to be related to changes in glomerular permeability. Several studies found that increased urinary albumin excretion rate is a sensitive indicator for early diabetic nephropathy. But, earlier indicators of impending diabetic nephropathy are needed, these are unlike microalbuminuria, would predict the subsequent development of diabetic nephropathy but instead the earliest sign of the nephropathy, haptoglobin used as a predictor in this study for patients with diabetic nephropathy and non nephropathic patients. In our study, there was a significant difference of haptoglobin level between patients and controls. Also, there is a significant difference between nephropathic and non nephropathic group. Also, there was a significant difference between macroalbuminuric, microalbuminuric and normolbuminuric groups.