Iron Status as a Comorbid Factor in Patients with Chronic Liver Diseases
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Serum iron is elevated in patients with chronic liver diseases. This study aims to evaluate the role of iron overload status in chronic liver diseases. Serum iron, serum ferritin, serum transferrin, liver functions tests and hepatitis markers were determined in 90 patients who have various chronic liver diseases [hepatitis B virus (REV), hepatitis C virus (HCV), hepatocellular carcinoma (HCC), mixed infection and pure schistosomal fibrosis] divided into 5 groups. Ascitic fluid samples were examined in a subgroup of 40 patients who have ascites. Results showed a high level of serum iron and ferritin in all groups. There was a positive correlation between serum transaminase, serum iron and serum ferritin. There was no significant correlation between liver iron content and serum iron, serum ferritin and serum transferrin in all groups. In patients with spontaneous bacterial peritonitis (SBP) ascitic fluid transferrin level was low.