THE EFFECT OF VITAMINE C SUPPLEMENTATHON ON GLUCOSE TOLERANCE IN UREMIC PATIENTS UNDER MAINTENANCE HAEMODIALYSIS
|Full paper||Not Available|
This study included 30 patients with end stage renal disease under regular haemodialysis Non of the patients had history of diabetes mellitus before haemodialysis. Patients were subjected to history taking and full clinical examination and the following investigations. Haematocrite value, blood urea, serum creatinine before and after haemodialysis. Intravenous glucose tolerance test a) before haemodialysis. h) after haemodialysis, c) after haemodialysis, during which vitamine C was supplemented in the form of ampules 500 mg ascorbic acid. One ampule in 100 ml saline infused during dialysis for 15 patients over a period of 4 hours (group 1). In group 11(15 patients) vitamine C was supplemented orally (100 mg/day) for a period of 4 weeks. Ascorbic acid levels in plasma were determined. Haemodialysis was found to cause deterioration in glucose metabolism which was found to he more reduced hut insignificant by intravenous ascorbic acid administration during dialysis session.