Can nabinoids And Male Fertility
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In spite of the evidence suggesting that many cannabinoid addicts are victims of infertility, Vet there is little inforniation about the extent of fertility affection and whether it is uniform on all fertility parameters or not. In order to clarify these issues, the effects of acute and chronic cannabinoid agonist (bango) inhalation on. different semen parameters, serum gonadotrophins, prolactin levels and testicular functions were studied. The results of this study revealed that acute bango inhalation resulted in a statistically significant reduction in sperm viability (p-:0.05) and motility (p<0.05), decrease in serum LH (p<0.05) and prolactin (p<0.05) levels, while FSH showed insignificant changes (p>0.05). Chronic bango inhalation resulted in a statistically significant decrease in sperm cell count (p<0.001), viability (p<0.001), motility (p<0.001), increase in abnormal forms (p<0.001), decrease in serum LH (p<0.05) and prolactin (p<0.01) levels, while FSH showed insignificant changes (p>0.05). Chronic bango inhalation caused a marked degenerative changes and depletion of spermatogenic cells in most seminiferous tubules augmented by concomitant inhalation of tobacco and bango which did not return back to normal levels after 30 days of treatment termination. In conclusion, bango inhalation has a serious deleterious effects on male fertility and sex hormones.