Abstract
This study was designed to evaluate the lead induced toxic effects on
the ultrastructure of adult rat Bowman's capsule, and comprised 18 rats.
The animals were divided into two equal groups, (n=9): control group given
pure distilled water and study group given a 0.13% lead acetate solution
in drinking water. After8 weeks exposure, rats were sacrificed and
their kidneys were removed and a small piece of renal cortex was fixed
and sections were prepared for electron microscopic examination. The
parietal cells of Bowman's capsule of the experimental group showed
signs of damage to nucleus and organelles, with abundance of cytoplasmic
vacuoles and phagolysosornes. We can conclude that exposure to
lead can induce damage to the parietal cells of Bowman's capsule in |
