Publications of Faculty of Medicine:Diagnostic Approach Of Non-Mass Forming Breast Calcifications: Abstract

Diagnostic Approach Of Non-Mass Forming Breast Calcifications
Full paper Not Available

Purposes: To evaluate diagnostic approach of non-mass forming breast calcifications, to find out correlation between Age of the patients and Morphology of calcifications. (Benign or malignant) and how to avoid unnecessary interventions. Background: Micro calcification diagnosis is challenged by presence of dense parenchyma resulting in low specificity values and unnecessary biopsies. Patients and methods: The study included 85 female patients; between 23-52 years age range divided into; Group A: 30 (35%) 35years old and Group B: 55 (65%) >35 years old. All patients undergoing Mammography, Guided biopsy (US. Guided FNAC was done for 12 cases where trucut biopsy was contraindicated) or Trucut wide bore biopsy using automated gun-shot and Surgical biopsy (by Hook-wire needle localization). Results: There were satisfactory results obtained by mammography in detection of benign calcifications; 38 (45%) cases (13% in group A & 32% in group B) and its sensitivity increased with age; (P-Value =0.03).Guided biopsy diagnosed 36 (76.6%) cases out of 47 as benign while 33 (70.2%) out of 47 were diagnosed benign after surgical biopsy i.e. Total benign calcifications were 71(84%) cases out of 85. Conclusions: Mammography is essential document for detection of benign calcifications. Use of FNAC is not recommended. Core biopsy plays important role to diagnose majority of calcifications; despite its disadvantages in certain cases. But surgical biopsy is the most accurate to diagnose all calcifications; despite its disadvantages are cost and lengthened procedure. Most of breast calcifications are benign but malignant calcifications are diagnosed by biopsy. Key words: Breast, Benign or malignant calcifications, No mass, Diagnostic approach.