Effects Of Unilateral And Bilateral Ligation Of Testicular Vessels On The Adult Rat Testis
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Abstract Testicular ischaemia has been implicated in the etiology of testicular pathology that causes male infertility. This study was designed to investigate the ultrastructural changes in both testes of the rat after bilateral ligation of testicular vessels and the changes in the contralateral testis after unilateral ligation. Thirty adult male albino rats were used in this study and were equally divided into three groups; Sham operated animals (control group), animals with bilaterally ligated testicular vessels and animals with unilaterally ligated testicular vessels. The animals were left for 6o days after ligation and the testes were then collected from each animal and were prepared for both light and electron microscopic study. Bilateral ligation of testicular vessels led to degenerative changes in the seminiferous tubules and the latter contained degenerated spermatognia and many inflammatory cells. The interstitium of the testis contained normal Leydig cells surrounded with dense connective tissue fibres. On the other hand, unilateral ligation of testicular vessels had no effects on the contralateral testis. In conclusion, these results showed that bilateral ligation of testicular vessels caused massive necrotic changes in both testes, while unilateral ligation gave no contralateral testicular changes.