LATE EFFECTS OF VASECTOMY ON THE TESTIS AHD EPHHOYMIS OF THE RAT
|Full paper||Not Available|
The structure of the testis and epididymal epithelium of the rat were studied at 5 months after bilateral vasectomy. The rat was chosen because this animal model can develop antisperm antibodies and display testicular as well as epididymal changes after vasectomy. Vasectomy operation was done via the process of division and ligation of the vas deferens. It is the most popular method of permanent male sterilization with a success rate of nearly 100%. Because of the increasing use of vasectomy in human (in some counteries), it is important to determine the effects of this surgical operation on the parts of the male reproductive system other than the vas deferens. The histological changes affecting the testis after vasectomy were depletion of most of the germinal epithelium, formation of large vesicles with heterogenous material in sertoli cells. While the epididymal epithelium showed vacuolations, the clear cells became enlarged and bulged into the lumen. The cytoplasm of the macrophages contain engulfed spermatic parts. The intersitital reactions were more prominent.