PRIMARY HEPATIC TUMOURS: CLINICOPATHOLOGICAL STUDY
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This study included 56 patients with primary liver tumours, presented to Cairo NCI. Fifty patients bad hepatocellular carcinoma (HCC). 4 cholangiocarcinoma and 2 hepatoblastoma. History. physical examination, laboratory and radiological investigations. including ultrasonogmphy and a were done for all patients. Hepatic angiography and 99 TC liver scanning were done in only 10 patients. Twenty one patients with HCC were explored : left hepatic lobectomy was done in 5 cases, right hepatic lobectomy in 2 cases and trisegmentectomy in 2 cases. Two patients with cholangiocarcinoma were explored, trisegmentectomy was done in one patients. The 2 cases with hepatoblastoma were resected after initial chemotherapy. Ten patients received systemic I.V. chemotherapy and 2 patients received intra-arterial chemotherapy. Ninteen patients did not receive any curvative treatment The median survival of the resected group was 14 months, chemotherapy group 3.6 months and 1.5 months in the "Not treatment" group. The low resectability, high mortality and low survival rates in this-series was due to high percentage of liver cirrhosis and relatively locally advanced disease. Early detection, new techniques of hepatic resection and new effective chemotheraputies may improve the outcome of this disease.