LIPID PEROXIDES, SUPEROXIDE DISMUTASE, GLUTATHIONE PEROXIDASE AND SELENIUM INRHEUMATOID ARTHRITIS
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Lipid peroxides, superoxide dismutase (SOD), glutathione peroxidase(GPX) and selenium were studied in 30 patients suffering from rheumatoid arthritis (RA). The study also included 15 apparently healthy individuals served as a control group. Lipid peroxides was significantly increased in RA patients as compared to the control group, meanwhile, SOD, GPX and Selenium were significantly decreased in RA patients as compared to the control group. As regards RA disease activity, we found that the level of selenium was significantly decreased in more active patients, so it can be considered as a marker of disease activity, while there were no significant differences in the levels of SOD, GPX and lipid peroxide as regards disease activity. By correlation coefficient, no significant differences were found between all the parameters in RA patients.