ROLE OF MAGNETIC RESONANCE IMAGING IN DIAGNOSIS OF BONE MARROW INFILTRATIVE LESIONS
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Background and Aim : MRI can detect intramedullary infiltration in a manner that has never seen before. It is also useful in detection of tumor extension, associated soft tissue masses and neurological compromise. MRI can increase the rate of successful bone marrow biopsies as it can assess a large volume of bone marrow non-invasively and relatively quickly .The aim of this study is to assess the role of MRI in the evaluation of bone marrow infiltrative lesions. Patients and Methods: This study included 30 patients with bone marrow infiltrative lesions; they were 14 males and 16 females. Age of the patients ranged from 8 to 75 years, (mean 41.5 years).Pain was the commonest symptom in the studied cases followed by swelling .Patients in our study were examined by plain radiography (15 cases), computed tomography (5 cases), isotopic bone scan in (1 case) and magnetic resonance imaging (all cases). Results: According to the pathological and radiological results, The lesions in our study are classified into: Metastasis (12 cases) - Plasma cell dyscrasias (8 cases), including: Multiple myeloma (6 cases) Plasmacytoma (2 cases) - Lymphoma (7 cases), including: Non Hodgkin's lymphoma (5 cases) Hodgkin's lymphoma (2 cases) - Ewing's sarcoma (2 cases) - Leukemia (Chronic lymphatic leukemia) (1 case) Conclusion: MRI is a sensitive method for detection of areas of marrow infiltration. The value of MRI lies in its ability to document the presence and extent of disease and determining an appropriate radiation field.