SCREENING FOR COLORECTAL CANCER WITH VIRTUAL COLONOSCOPY
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Purpose: to rule out the role of Multislice Helical CT (MSCT) in screening of colorectal cancer as it allows high-speed acquisition of truly volumetric datasets, it also describes the combination of colonic imaging with surface extraction and rendering of the gas-mucosal interface which simulates the view obtained during conventional fibro-optic video-endoscopy. Material and methods: (60) patients (51) men, (9) women; age range, (45-75) years were included in this study. Patients eligible for inclusion were those who were seen in a gastroenterology clinic and were scheduled for colonoscopic evaluation because of a positive fecal occult blood test, iron deficiency anemia, hematochezia, or a family history of polyps. No patient was known to have polyps. CT colonography was performed first, and colonoscopy was performed 3 hours later. Results: In a comparison of MSCT-colonography with endoscopic colonoscopy in 60 patients referred for exclusion or early diagnosis of colorectal cancer, MSCT-colonography detected a total of 32 of 38 polyps (84%) and 2 Of 2 carcinoma (100%). All polyps greater than 10 mm were detected ( 6 of 6 polyps), 8 of 8 polyps ranging from 6 to 9 mm and 18 of 24 polyps smaller than 6 mm were identified. 26 false positive finding affected 16 patients. 6 false negative finding affect two patients, results are summarized in table 1. Conclusion: with thin-section low-dose multi—detector row CT colonography, there is excellent sensitivity and depiction of large colorectal polyps. Ultimately, low-dose thin-section multi—detector row CT colonography, by facilitating decreased radiation doses and decrease false-positive rates while maintaining excellent sensitivity for detection of large polyps, may lead to increased patient and clinician acceptance of the use of this examination.