Is Modified Radical Mastectomy of Patey Equivalent to Radical Mastectomy in Treatment of Operable Breast Carcinoma?: An Evaluation Study
|Full paper||Not Available|
Sixty female patients diagnosed as operable breast cancer were subjected to either radical mastectomy (first group) or to modified radical mastectomy of Patey's (second group) in a randomized study. Each group included 30 patients. Their mean ages were 42 4 5 years and 44 4 3 years in both groups respectively. Postoperative adjuvant radiotherapy and systemic therapy (hormonal and chemotherapy) were given when indicated. All patients were followed up from 24 to 36 months. Axillary clearance showed that the number of dissected nodes were 10-22 (mean 1543) and 12-22 (mean 1444) in both groups respectively. No operative mortality occurred in either group. Early post-operative complications were 30% after radical mastectomy and 10% after modified radical mastectomy; seroma in (10%) and (3.3%), wound infection in 13.3% and 6.6% in both groups respectively. Skin flap necrosis was observed in 6.6% in the first group and not occurred to any of the second groups. Late post-operative complication were 23.3% in the first group and (6.6%) in the second group; lymphoedema in 20% and (3.3%) in both groups respectively: radiation pneumonitis occurred in 3.3% after radical mastectomy, while radiation dermatitis occurred in 3.3% after modified radical mastectomy. Locoregional recurrences occurred in 6.6% in either group, while distant metastases occurred in 16.6% after radical mastectomy and in (20%) after modified radical mastectomy. The overall survival was 90% in the first group and 86.7% in the second group; while the disease free survival was 76.7% and 73.4% in both groups respectively during the period of follow up. In conclusion, modified radical mastectomy of Patey is as effective as radical mastectomy regarding the locoregional control of the'disiease, disease free survival and the overall survival. It has less morbidity,' better cosmetic, functional and psychological results. Therefore, we recommend the use of modified radical mastectomy of Patey for treating patients with operable breast carcinoma.