PROPHYLACTIC TREATMENT OF INTRAOCULAR PRESSURE ELEVATIONS AFTER NEODYMIUM: YAG LASER POSTERIOR CAPSULOTOMY
|Full paper||Not Available|
To compare the efficacy and safety of topical 2.0% dorzolamide hydrochloride, topical 0.5% levoburtolol and oral acetazolarnicle in preventing intraocular pressure (10P) rise following neodymium: YAG (Ncb YAG) laser posterior capsulotomy. Forty eyes of forty patients were enrolled in this prospective, random- :zed, placebo-controlled study. Pretreatment with dorzolamide, levobunclot, acetazolamide or placebo was given 1 hour before capsulotomy. The dose of treatment was 1 drop (approx. 20 p L) for any of the topical eye drops (i.e. dorzolamide, levobunolol or placebo) and a single dose of 125 mg acetozolamicle. At first and third hour postoperatively, 10Ps and 10P change from baseline were significantly (P < 0.001) higher in the placebo group than in any of the treated groups. No patient treated with dorzolamtde, levobuno- Lot or acetozolcunide experienced an 10P higher than 30 mmFlg after capsulotomy, but 60% of patients receiving placebo had an 1013 above this level (P < 0.001). No serious side effects were recorded in any of the studied patients.