Quadruple Approach for the Treatment of Persistent Silicone Oil - La L4 situ ISA 414.•
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Purpose; Was to provide a solution to the problem of persistent silicone oil induced glaucoma (SOIG), which represents a common type of intractable glaucoma that usually adds to the hazards of complicated vitreoretinal surgeries. The trial aimed to evaluate the efficacy and safety of a quadruple approach of combined lines of glaucoma treatment. Methods 17 eyes of 17 patients presented with SOIG were included in this controlled non- randomized prospective clinical trial. All eyes underwent trabeculectomy with intraoperative mitomycin-c (MMC) application plus bevacizumab injection (1.25mg) together with early postoperative topical MMC drops (0.03mg/m1). Trans-scleral diode cyclophotocoagulation (TSDCP) was applied late when indicated The main outcome results included cumulative probability of surgical success, lOP values, number of antiglaucoma drugs needed. and BC VA.