Publications of Faculty of Medicine:ROLE OF DELAYED PHASE MULTI—DETECTOR ROW HELICAL CT IN PATIENTS WITH HEPATOCELLULAR CARCINOMA: Abstract

Title:
ROLE OF DELAYED PHASE MULTI—DETECTOR ROW HELICAL CT IN PATIENTS WITH HEPATOCELLULAR CARCINOMA
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Abstract:

Objective: The purpose of this study is to determine the added diagnostic value of the delayed venous phase in diagnosing hepatocellular carcinoma (HCC) using a mu! idetector helical CT scanning in conjunction with hepatic arterial and portal venous phases. Patients am! Methods: Thirty six patients with suspected FICC after ultmsonographic examination underwent MDCT imaging. A total number of 62 biopsy-approved HCC lesions were included in this study, 58 lesions were sonographically detected, and extra four lesions were detected only after triphasic MDCT scanning. Images were interpreted regarding the size, homogeneity, pattern of enhancement, hypervascularity and washout, capsule, abnormal internal vessels. calcifications. fat and central scar. Results: Most of the HCCs were hypervascular (91.2%) exhibiting mosaic pattern of enhancement on the hepatic arterial and portal venous phases (82.5%, and 78.9% respectively). Portal venous phase washout accounted for 76.9% of hypervascular FICCs. Capsulated lesions accounted for 27.1%; 56.3% of these capsules were identified on the delayed phase only. The dttal-phase MDCT detected 57 (91.9%) out of the 62 lesions compared with the triple—phase MDCT where 59 (95.2%) lesions were detected. Two hepatocellular carcinomas (34%) were seen only in the delayed phase as hypoattenuating nodules. Conclusion: Delayed venous phase of hepatic CT is beneficial in detection and characterization of hepatocellular carcinoma, as it detected small, hypoattenuating, and capsulated hepatocellular carcinomas in a higher rate than biphasic imaging alone. Our results encourage the use of a triple-phase helical CT technique for the evaluation of patients with hypovascular hepatic HCCs. This technique is recommended to be performed especially in patients who are candidates fur curative partial hepatic resection or interventional management.

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