An Evaluation of aNewMethbd:!l for Bleomycin Intralesional Injectioni for the Treatment ofRecalcitrantWarts
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Intralesional injection of bleomycin has been reported effective in the treatment of recalcitrantwarts formany years. Many modifications had been made to avoid its var ious side effects. The aim of the present study was to determine the efficacy,^ safety and patient acceptance of a new method for introducing bleomycin into warts by pricking it with a needle into die wart in comparison with direct intralesional injection of 1% bleomycin sulphate solution in normal saline. We found that both tech- • nicjues are equally effective, with cure rates of 73.8% and 71.1% for the pricking and intralesional method respectively. Palmar warts had the best response while perilin^ gual warts were less responsive. Local pain was, on thewhole, well tolerated. No la boratory abnormalities were noticed after treatment. We conclude that the pricking method used for tratment of resistantwarts is reliable, safe and acceptable to patients. It will be more acceptable if an effective topical anesthetic is available instead of local injection anesthesia.