Treatment of alopecia areata (AA) is challenging, as the disease is
characterized by extreme variability not only in the time of initial
onset of hair loss but in duration, extent and pattern of hair loss during
any given episode of active loss, making a universal treatment
difficult to implement.
The present study was done to evaluate the efficacy of
intravenous pulse dexamethasone in treatment of extensive AA, and to
compare the efficacy of single course therapy versus that of three
courses therapy (monthly administrated).
Thirty patients with active extensive AA were included in this
study. Results showed that, intravenous pulse of dexamethasone is an
effective and well tolerated modality in the treatment of extensive,
active multifocal alopecia areata. Better response was obtained by
monthly repeated courses and in cases lasting less than 12 months. |
