STEROID PULSE THERAPY FOR THE TREATMENT OF EXTENSIVE ALOPECIA AREATA
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Treatment of alopecia areata (AA) is challenging, as the disease is characterized by extreme variability not only in the time of initial onset of hair loss but in duration, extent and pattern of hair loss during any given episode of active loss, making a universal treatment difficult to implement. The present study was done to evaluate the efficacy of intravenous pulse dexamethasone in treatment of extensive AA, and to compare the efficacy of single course therapy versus that of three courses therapy (monthly administrated). Thirty patients with active extensive AA were included in this study. Results showed that, intravenous pulse of dexamethasone is an effective and well tolerated modality in the treatment of extensive, active multifocal alopecia areata. Better response was obtained by monthly repeated courses and in cases lasting less than 12 months.