Histological, Histochemical and Steroidogenic studies on the effect of euthyroid, hypothyroid and hyperthyroid on the testis of male adult albino rats
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Until a few years ago, the testis was considered to be unresponsive to thyroid hormones. Recently T3 receptors located in the nuclei of Sertoli and Leydig cells of the rat testis have been shown to increase during the fetal and perinatal periods, and tend to decrease until puberty. In this study, we investigated the histological, histochemical and steroidogenic of the testis in euthyroid, hypothyroid and hyperthyroid adult rats, to detect whether the deficiency of 13 receptors in adult testicular tissue prevents the thyroid hormone effects on the testis or not. 30 adult's male albino rats were used in this study. Many histological and histochemical changes were observed. Also, testicular weights were significantly increased in hyperthyroid and decreased in hypothyroid rats. These results indicate that thyroid hormones still can regulate the testicular functions in spite of deficiency of 13 receptors in the testis of adult rats.