STUDY OF THE HAEMODYNAMICS AND RESPIRATORY CHANGES DURING TOTAL INTRAVENOUS ANAESTHETIC USING FENTANYL AND ICETAMINE
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Intravenous feritarug1 and ketamine in combination with pancuronium and oxygen for anaesthesia were used in 40 adult male pateints (ASA I and II) undergoing hernion-haphy surgery. All patients were premedicated with midazolam 8 mg and atropine 0.6 mg. Patients were divided into 2 groups according to drug used The mean fentanyl infusion rate required for sfinble anaesthesia was 4.8 + 1.2 ug /minute and the mean ketarnine infusion rate was 3.4 mg / minute The fentanyl group showed cardiovascular stability (heart rate, systolic, diastolic, mean arterial pressure and E. C. G.) during induction, skin incision and at the end of infusion compared with ketamine group which showed signcant (P < 0.05 - P < 0.01) increase in the above cardiovascular parameters. Arterial oxygen saturation P502 and ETco2 for both groups showed insignficant changes from the basal line. The recovery was smooth and the mean recovery time was (4± 1 minutes) after fentanyl and (16 + 4) minutes after ketamine infusion with no post operative complain from awarness.