Evaluation of different diagnostic methods in solitary thyroid nodule
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The term thyroid nodule refers to any abnormal growth of thyroid cells into a lump within the thyroid. Although the majority of thyroid nodules are benign (noncancerous), a small proportion of thyroid nodules(5-10%) do contain thyroid cancer. Because of this possibility, the goal of diagnostic workup is to select those patients who have a high likelihood of harbouring malignancy in the solitary thyroid nodule. The present study was undertaken to evaluate the efficacy of Fine Needle Aspiration Cytology (FNAC), Radionuclide Scan (RNS) and Conventional and Power Doppler Ultrasonography(USG) in differentiating between benign and malignant nodules. It was found that FNAC is a safe, reliable and cost effective diagnostic modality with a high sensitivity of 75% and specificity of 100% and is the single best investigation for preoperative evaluation of solitary thyroid nodules to differentiate between benign and malignant nodules.