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Dr. Amal Mohamed Hamed Mahmoud Abd Elkareem :: Publications:

Title:
the protective effect of garlic on changes in liver and brain proteins occurring in albino rats exposed to 900 mhz (gsm) microwaves
Authors: Sharaf-Eldeen, Kh. M.; Zowail, M. E. M. and Abdel-Kareim, A. M
Year: 2005
Keywords: Mobile phone, electrophoresis, protein, liver, brain, garlic
Journal: MEDICAL
Volume: VOL. XI,
Issue: 3
Pages: Not Available
Publisher: ZAGAZIG UNIVERSITY
Local/International: International
Paper Link: Not Available
Full paper Not Available
Supplementary materials Not Available
Abstract:

Garlic (Allium sativum ) has been used as a medicinal agent for thousands of years. In the present work the radioprotection of this agent will be investigated. Fourty five mature female albino rats, Rattus norvegicus were allotted into groups and exposed to mobile phone microwave (MP) of 900 MHz for 14, 30 or 45 days. The effect of garlic treatment in association with the MP exposure was also studied. Protein expression was examined in both liver and brain tissues by using SDS-polyacrylamide gel electrophoresis. The results showed that MP exposure caused induction of newly synthesized polypeptides in liver and brain tissues. On the other hand, the daily administration of 20mg/kg garlic decreased the number of protein fractions in liver while such fractions were increased in brain tissue and this effect was associated especially in liver tissue with expression of new proteins which maybe stress proteins; these proteins have low molecular weight. Also, garlic prevented significantly the depression of mitotic index (MI) that occurred under the effect of MP exposure. The present work suggested the in vivo radioprotective role, antimutagenic and anticarcinogenic effect of garlic.

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