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Prof. Evat Isaac :: Publications:

Novel synthesis of phthalazine derivatives as antimicrobial agents
Authors: Yvette Issac, Eman El-Karim, Shafie Donia, Mohamed Behalow
Year: 2002
Keywords: Not Available
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: International
Paper Link: Not Available
Full paper Not Available
Supplementary materials Not Available

Reaction of 4-(phenoxathiin-2-yl)-1-oxy or mercaptophthalazines 2a, c with phthalyl or tosylamino acids 3 and 4 has been found to yield 5, 6a-j. Hydrazinolysis of 5, 6a-e furnished amino derivatives 5, 6k-o. Some of the newly synthesized products were tested for their antimicrobial activities.

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