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Prof. Hussein Abd Elmaksoud Ali :: Publications:

Title:
Biochemical effect of Moringa peregrina Seeds on experimentally leukcytopenia in Rats
Authors: 1Abdel-Maksoud, H.A., 2Mohammed, A. Hussein, 1Afaf, D., Abd El Mageed and 1Wafaa Abd El Zaher Taha
Year: 2015
Keywords: Moringa seeds oil, 5-Flourourasil, benzene, leukopenia and antioxidants
Journal: BENHA VETERINARY MEDICAL JOURNAL
Volume: 29
Issue: 1
Pages: 151-163
Publisher: BENHA VETERINARY MEDICAL JOURNAL
Local/International: International
Paper Link:
Full paper Not Available
Supplementary materials Not Available
Abstract:

oil at dose of 381 mg/kg in 400mg/kg.b.w Benzene and/or 20 mg/kg.b.w 5-Flourourasil induced leukopenia rats 2 weeks after induction of leukopenia in rats, Moringa peregrina seeds oil at dose of 381 mg/kg was administrated for 30 consecutive days. On the 31th day, the rats were sacrificed for the estimation of Hemoglobin (Hb%), Total Leucocyte Count (WBC) and Platelet Count (PLT) as well as biochemical parameters; Alanine Transaminase (ALT), Aspartate Transaminase (AST), Alkaline Phosphatase (ALP), Albumin(Alb) , Total Protein, Lactate Dehydrogenase (LDH), Creatine Kinase (C.K), Urea , Creatinine ,Reduced Glutathione (GSH), Superoxide Dismutase (SOD), Catalase (CAT), Total Cholesterol (T.Ch), Triglycerides (TG), P53 Gene Expression, Nitric Oxide (NO) , Thiobarbituric Acid Reactive Substances (TBARs) and Tumor Necroses Factor-α (TNF-α). The results of this study also showed that administration of Moringa peregrina seeds oil at dose of 381 mg/kg.b.w to leukopenia induced rats demonstrated a significant (P

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