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Prof. Hussein Abd Elmaksoud Ali :: Publications:

Title:
Biochemical effects of chamomile oil on inflammatory biomarkers in gastroenteritis
Authors: Hussein AA and Mohamed GE , Lobna MS, Mohammed A
Year: 2017
Keywords: Gastroenteritis; Chamomile oil; Inflammatory biomarkers
Journal: International Journal of Drug Development and Research
Volume: 9
Issue: 2
Pages: 01-04
Publisher: insight medical publishing
Local/International: International
Paper Link:
Full paper Hussein Abd Elmaksoud Ali_biochemical-effects-of-chamomile-oil-on-inflammatory-biomarkers-ingastroenteritis.pdf
Supplementary materials Not Available
Abstract:

Gastroenteritis is a major health problem, especially in developing countries including Egypt. Chamomile has been used in the traditional medicine for the management of gastrointestinal disorders. The aim of this study was to evaluate biochemical alterations of inflammatory biomarkers in gastroenteritis after administration of chamomile oil. In order to achieve this aim 30 male albino rats was divided into two main groups, healthy control group and induced gastroenteritis group by using enteropathogenic E. coli. Half of them kept as positive control and the remaining treated with chamomile oil. The results of the present study showed a significant association between exposure to bacterial gastroenteritis and high level of inflammatory biomarkers like IL2, IL6, TNF, histamine and cortisol. The results also showed a significant decrease in inflammatory biomarkers IL2, IL6, TNF, histamine and cortisol in gastroenteritis group upon administration of chamomile oil. These findings suggested that chamomile oil possess anti-inflammatory activity confirming their traditional use.

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