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Prof. Mahassen Saad Amine :: Publications:

Title:
Synthesis of Some Azoles and Azines based based on quinoline -8-yloxy-acetohydraide
Authors: Abdelmetaal Abdelmged, Aly A.Aly, M.S.Amine and A.A.Ghith
Year: 2015
Keywords: quinoline, 8-yloxy acetohydrazide, quinoline-8-yloxy methyl oxadiazole acetohydrazide, pyrazole thiazole, oxazole, triazole, pyridazine, phthalazine, isatine and antimicrobial activity.
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: International
Paper Link: Not Available
Full paper Not Available
Supplementary materials Not Available
Abstract:

A new Azoles and Azines as pyrazole, thiazole, oxadiazole, triazole, pyridazine and phthalazine based on quinolone moiety efficiently synthesized via very simple and efficient chemical reactions of quinolone-8-yloxy acetohydrazide and quinolone-8-yloxy methyl oxadiazole acetohydrazide with electrophilic reagents in base medium using simple techniques and reagents. The structures of the new synthesized products were deduced based on their analytical, spectral data and by using the fragmentation pattern as a tool for supporting the chemical structure also, the biological activity of the synthesized compounds as antimicrobial and antifungal were screened.

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