Hypertrophic scars and keloids are pathological scars which are problematic in treatment. Many treatment modalities have been described including pressure therapy, surgical revision, laser therapy, silicone garments, and intralesional drug treatments.
The aim of this study was to evaluate the effect of Nd:YAG laser alone or in combination with intralesional injection of botulinum toxin type A and intralesional injection of steroid in treatment of HTS.
This was a randomized controlled study that included 45 patients with HTSs with no history of treatment prior to the study. Patients were randomized into three study groups, group I (Nd:YAG laser alone), group II (Nd:YAG laser followed by intralesional injection of steroid), and group III (Nd:YAG laser followed by intralesional injection of botulinum toxin type A).
All patients received a course of four treatment sessions of laser therapy at one-month intervals. Photography, clinical improvement assessment by VSS, patients′ symptoms and satisfaction assessment by PSAS were done for each patient before and three months after the last session.
The results of our study were as follow:
Compared to baseline, there was a significant reduction in the VSS three months after the last treatment session in all groups (P |
