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Prof. Mohamed El Sayed Sobhey Abosalem :: Publications:

Title:
TOXICOLOGICAL EFFECT OF COPPER SULPHATE AND COBALT CHLORIDE AS FEED ADDITIVES ON FERTILITY IN MALE ALBINO RATS
Authors: Saida A Mohamed, HH Bakry, ME Abou Salem, Nabila A M, Elham A E
Year: 2014
Keywords: Not Available
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: Local
Paper Link: Not Available
Full paper Mohamed El- Sayed Sobhey Abou Salem_COPPER SULPHATE AND COBALT TOX.pdf
Abstract:

This study is designed to investigate the effect of copper sulphate and cobalt chloride, which are used as additives in feed on fertility of male white albino rats. One hundred rats classified to five groups. First group used as control; second and third group were given 1/10 and 1/5 LD50 of CuSo4 respectively, fourth and fifth groups were given 1/10 and 1/5 LD50 of CoCl2 respectively (orally via stomach tube). Testis and epididymis were dissected and used for detection of sperm motility and counts. Histopathological examination was performed on testis. Results showed significant decrease in testis and epididymis weight and significant increase on sperm abnormalities while sperm numbers were significantly decreased. It can be concluded that ingestion of copper sulphate and cobalt chloride in high doses decrease fertility in male albino rats. Key words: cobalt toxicity- copper toxicity – spermatogenesis- heavy metals.

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