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Prof. Naglaa Fathy Ibraheem Al-Husseini :: Publications:

Title:
Telomere Length Measurement by Quantitative Real-time PCR: A Molecular Marker for Human Age Prediction
Authors: Naglaa F. Alhusseini and Abdelmonem G. Madboly
Year: 2016
Keywords: Not Available
Journal: american journal of biochemistry and molecular biology
Volume: 12
Issue: 1
Pages: 64-71
Publisher: science publication
Local/International: International
Paper Link:
Full paper Not Available
Supplementary materials Not Available
Abstract:

The fact that telomere shortening occurs with aging leads to the hypothesis that a correlation could be made between Telomere Length (TL) and suspect age. This study aimed to assess if TL can be used as an investigational tool to predict human age through developing a formula based on this correlation with accuracy suitable to be applied in forensic practice. A quantitative real-time PCR study was carried out on 80 Egyptians, ranging in age from 1-79 years. The results confirmed that the relative TL significantly shortened with aging; “r” = -0.903 (p

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