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Dr. SAMAH EZZAT IBRAHIM SHERIF :: Publications:

Title:
Evaluation of Plasma microRNA-33 in Psoriatic Patients and its correlation with insulin resistance and common carotid artery intima-media wall thickness
Authors: Dr. Abd El-Aziz Ibrahim Abd El-Aziz El-Taweel ,Dr. Hanan Hassan Sabry,Dr. Jihan Hassan Sabry Samah Ezzat Ibahim Sherif
Year: 2019
Keywords: Psoriasis, miRNA-33, Insulin resistance, Carotid intima media thickness
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: 149
Publisher: Not Available
Local/International: Local
Paper Link: Not Available
Full paper SAMAH EZZAT IBRAHIM SHERIF_08 Chapter I.docx
Supplementary materials SAMAH EZZAT IBRAHIM SHERIF_09 Chapter II.docx
Abstract:

Psoriatic patients exhibited more atherogenic lipid profile, higher CIMT and HOMA-IR values than healthy individuals. MiR-33 is significantly elevated in plasma of psoriatic patients and is correlated with PASI score. Moreover, MiR-33 is positively correlated with HOMA-IR and CIMT. In conclusion, miRNA-33 can be used as potential biomarker for psoriasis and as a predictor for cardiovascular comorbidity as increased insulin resistance and subclinical atherosclerosis in psoriatic patients.

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