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Dr. SAMAH EZZAT IBRAHIM SHERIF :: Publications: |
Title: | Evaluation of Plasma microRNA-33 in Psoriatic Patients and its correlation with insulin resistance and common carotid artery intima-media wall thickness |
Authors: | Dr. Abd El-Aziz Ibrahim Abd El-Aziz El-Taweel ,Dr. Hanan Hassan Sabry,Dr. Jihan Hassan Sabry Samah Ezzat Ibahim Sherif |
Year: | 2019 |
Keywords: | Psoriasis, miRNA-33, Insulin resistance, Carotid intima media thickness |
Journal: | Not Available |
Volume: | Not Available |
Issue: | Not Available |
Pages: | 149 |
Publisher: | Not Available |
Local/International: | Local |
Paper Link: | Not Available |
Full paper | SAMAH EZZAT IBRAHIM SHERIF_08 Chapter I.docx |
Supplementary materials | SAMAH EZZAT IBRAHIM SHERIF_09 Chapter II.docx |
Abstract: |
Psoriatic patients exhibited more atherogenic lipid profile, higher CIMT and HOMA-IR values than healthy individuals. MiR-33 is significantly elevated in plasma of psoriatic patients and is correlated with PASI score. Moreover, MiR-33 is positively correlated with HOMA-IR and CIMT. In conclusion, miRNA-33 can be used as potential biomarker for psoriasis and as a predictor for cardiovascular comorbidity as increased insulin resistance and subclinical atherosclerosis in psoriatic patients. |