Page Preview: 61

Course Title[Course Code]:Quantitative Genetics (Advanced)[Gen 704]

Faculty: Agriculture
Department: Genetics
Program: Molecular and Biochemical Genetics
Compulsory / Elective:Compulsory
Postgraduate(Doctoral-First Semester or Second Semester)
Hours:
Lecture:( 2 ) Practical / Clinical:( 2 ) Tutorial:( - )

Course Description:
Quantitative inheritance: traits controlled by many loci; two, three and multi-locus control; location of polygenes and significance of polygenic inheritance; QTL mapping using molecular marker, population statistics; heritability; realized heritability; partitioning of the variance; measurement of heritability; quantitative inheritance in human beings; Population Genetics: populations, gene pool, gene frequency; Hardy-Weinberg law; the Hardy- Weinberg equilibrium and mating systems; estimation of gene frequencies; causes of changes in gene frequency; concepts and rate of change in gene frequency through natural selection, artificial selection; Heritability, Quantifying heritability; proof of Hardy-Weinberg equilibrium; generation time; testing for fit to Hardy-Weinberg equilibrium; extensions of H-W equilibrium-multiple alleles, multiple loci; Non random mating- inbreeding, pedigree analysis and population analysis; migration and random genetic drift; adaptive radiation and modifications; isolating mechanisms; speciation; allopatricity and sympatricity; convergent evolution; sexual selection; co-evolution; Evolutionary forces; processes that change allelic frequencies: models for population genetics; change of gene frequency under mutation, migration and different types of selection;