In attempting to find drugs effective in preventing and remedying
ototoxic injury caused by aminoglycoside antibiotics, Nigella Sativa was
selected from the traditional Egyptian herbal medicine and the effect on
the pattern of gentamicin ototoxicity in guinea pigs was observed. The
results indicated that Nigella Sativa possessed the definite effect of
protecting the guinea pigs cochlea. Observation of renal morphology
showed that it also protected the kidney against toxic nephritis of
gentamicin. |
