The effect ofinfection by Chlamydia pneumoniae (C. pneumoniae) and
Helicobacter pylori (H pylori) on patients with coronary heart diseases
(CHD) was investigated. 40 patients; 20 sufferedfrom acute myocardial
infarction (AMI) (Group I) and 20 sufferedfromangina (Group n) were se
lected as patient groups. 20 clinically healthy persons of the same age
were selected as acontrol group (Group IE). The patientgroups were subgrouped
according to the most important riskfactors for CHD (smoking,
hypertension, and hypercholesterolaemia). The level ofC.pneumoniae igG
&igMandH.pylori IgG were detected inthe sera ofthe three groups.
It wasfound that C.pneumoniae IgG was positive in 18%, 14%, and
4%with mean Hire 364. 8, 380.7, 12.8 (in groups I,E, and El respectively)
which was significantly higher in group I and II than group IE.
C.pneumoniae IgMwas negative ingroups I and IE, while itwas positive
in 15% ofgroup E with mean titre 275.6 with a statistical significance
among the three groups. H.pylori IgG was positive in 60%. 50%, and 45%
withmean concentration 312.2, 315.4, and 151.3 on groups I, E, and IE
(respectively) with insignificant difference among the three groups.
As regards to smoking status, C.pneumoniae IgGwas higher in smok
ers than in non-smokers in groups I andEwith significant difference in
group I only. C.pneumoniae IgMwas insignificant in bothgroups.H.pylori
IgG was high in smokers in both groups with non significant difference.
Concerning blood pressure, C.pneumoniae IgG, IgMand H.pylori IgG in
both groups were high in hypertensives with no significant relation
among them. |
