Publications of Faculty of Medicine:THE PROTECTIVE EFFECT OF L. ARGENINE ON CEREBRAL INFARCTION INDUCED IN RATS: Abstract

Title:
THE PROTECTIVE EFFECT OF L. ARGENINE ON CEREBRAL INFARCTION INDUCED IN RATS
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Abstract:

The cerebral protective effect of L. Argenine was assessed on cerebral infarction induced in rats by ligation of the common carotid artery. The degree of protection was determined biochemically by measuring level of serum creatine phospholdnase enzyme (CPK) and histopathologically, by estimating the percentage of infarcted size (1.5%). In rats treated with L Argenine (60 'tug/ Kg / LP) 10 minutes after induction of infarction. serum CPK, infarcted size % were significantly decreased compared with infarcted non treated group (P In conclusion. L-Argenine could protect the brain against extension of infarcted size.