Few inconclusive studies were done to evaluate the antimicrobial
effect of low energy laser therapy (LELT). This study was done to
evaluate the effect of LELT (with and without a photosensitiser) on
infected wounds in guinea pigs. A traingular .wound in the dorsal aspect
of 60 guinea pigs was made and infected by staphylococcus aureus. They
were randomly divided into 4 groups after 24 hours. Group (I) was
treated daily with LELT (dose: 43.2 J/cm2) and toluidine blue 0 as a
photosensitiser at a concentration of 12.5 pg/ml. Group (II) received
LELT only at the same dose as in group (I). Group (III) was treated
conventionally with Betadine soaked sterile gauze daily. group (IV) had
no treatment to act as a control. We found that LELT with toluidine blue
0 produced the best significant results compared to the other groups
with regard to anti-bacterial activity, purulence reduction and wound
healing This effective, safe, painless and non-touch technique deserves
to be considered in the management of infected wounds |
