Aim of the Work: The aim of this work was to study the usefulness or serum CRP as a systemic inflammatory marker for COPD patients and to evaluate ischemic heart diseases (IHD) and smoking as potential causes of raised CRP levels in CORD.
Subjects and Methods: Forty male patients with COPD were admitted to chest department. Benha University Hospital were included in this study and 40 healthy male of the same age and sex as a control group (20 smokers and 20 nonsmokers) with no history of ischemic heart diseases and with normal ventilatory function tests. The patients and controls were subjected for full clinical evaluation including a full clinical and family history. History of any other co-morbidities that may raise the C-reactive protein as ischemic heart diseases, hypertension. diabetes mellitus, tuberculosis, malignancy, hepatic cirrhosis, end-stage renal disease, rheumatoid arthritis and any systemic infection or inflammation that could be associated with increased CRP values. General & local examination, routine laboratory tests, plain chest X-ray (P.A. and lateral view), Body mass index. Pulmonary function tests (spirometry) before and after bronchodilatation. Electrocardiography, complete blood count, liver function tests, kidney function tests and fasting blood sugar and venous blood samples for C-reactive protein measurement |
