Publications of Faculty of Medicine:ASSESSMENT OF CARDIAC FUNCTIONS BEFORE AND AFTER EXERCISE IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE : Abstract

Title:
ASSESSMENT OF CARDIAC FUNCTIONS BEFORE AND AFTER EXERCISE IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
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Abstract:

To assess the right and left ventricular performance in patients with COPD, fifty subjects were included; 40 COPD patients and 10 apparently healthy control subjects. Exclusion criteria were any history of systemic hypertension, ischemic or valvular heart disease or episodes of right and/or left sided cardiac failure. Ventilatory pulmonary function tests, echo-Doppler examination and exercise test was done for all subjects. It was concluded that in COPD patients FEV I% was 31± 6.85 and FEV I/FVC% was 56.55 ± 7.67. The right and left ventricular systolic functions assessed by ejection fraction were preserved at rest. After exercise it was preserved in the left ventricle but significantly deteriorated in the right ventricle in COPD group than in the control group (P < 0.01). As regards the diastolic functions of both ventricles assessed by E/A ratio, it was deteriorated at rest (P<0.05) and became more deteriorated after exercise (P<0.01). Mean pulmonary pressure (MPP) was high at rest and became higher after exercise. There was significant positive correlation between ventilatory functions and left ventricular diastolic function. There