Intravenous fentanyl and ketamine in combination with pancuroniurn and oxygen for anaesthesia were used in 40 adult male patients (AM I and II) undergoing herniorrhaphy surgery. AU patients were premedicated with midazolam 8 mg and atropine 0.6 mg. Patients were divided into 2 groups according to drug used. The mean fentanyl infusion rate required or stable anaesthesia was 4.8 ± 1.2 uglminute and the mean ketamine infusion rate was 3.4 mg/minute. The fentan)! group showed cardiovascular stability heart rate, systolic, diastolic, mean arterial pressure and E.C.G.) during induction, skin incision and at the end of infusion compared with ketamine group which showed significant (P < 0.05 - P <0.01) increase in the above cardiovascular parameters. Arterial oxygen saturation Sao2 and El' Co2 for both groups showed insignificant changes from the basal line. The recovery was smooth and the mean recovery time was (4 ± 1 minutes) after fentanyl and (16 ± 4)minutes after ketamine infusion with no post operative complain for awareness |