Posttransplantation diabetes mellitus IPTDM) is a major medical problem that adversely affect the recipient and the graft after renal transplantation. Its exact incidence has been difficult to determine among previous studies. This study was done on 1558 patients received live donor renal allograft. 286 patients (18.2%) developed PIDM and they constitute the patient group that was studied against a control group of 316 nondiabetic recipient. The study showed that the incidence of PTDM was highest during the first 6 months posttransplantation. The main risk factors were : older recipient age, positive family history of diabetes mellitus, obesity, the use of calcineurin inhibitors, the total teroid dose and HCV infection. It adversely affect the patient survival and the graft function and is responsible for many medical compl ications that affect the recipient. |
