Publications of Faculty of Medicine:CIRCULATING T-CELL SUBSETS AND IMMUNOGLOBULINS LEVEL IN PATIENTS WITH PULMONARY TUBERCULOSIS: Abstract

Title:
CIRCULATING T-CELL SUBSETS AND IMMUNOGLOBULINS LEVEL IN PATIENTS WITH PULMONARY TUBERCULOSIS
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Abstract:

T- lymphocyte subpopulation (T3, T4 and T8) and serum imrnunoglobu- /ins (Ig G. IgA. and Ig M) were estimated in blood of (20) patients with active pulmonary tuberculosis (group I-a), (20) patients With inactive pulmonary tuberculosis (group I-b) and (10) healthy persons (group II). All ubjects were assessed clinically, radiologically, bacteriologically and by tuberculin testing. Active tuberculosis (group I-a) was associated with significant increase in 12 G and Ig M levels, insignifcant increase in Ig A level, highly signifcant decrease of absolute total lymphocytes. insignificant decrease of T 3%, highly signifeant decrease of absolute T3. highly signif cant decrease of T4% and absolute T4, highly signifcant increase of T8 and highly signifcant decrease of T4/ T8 ratio. Patients with inactive ulmonary tuberculosis (group I-b) showed near normal values of serum immunoglobultris (Ig G, M and A). T3, T4, T8 and T4/T8 ratio.