Publications of Faculty of Medicine:PERICARDIAL EFFUSION AND LEFT VENTRICULAR DYSFUNCTION IN PATIENTS WITH HEPATIC CIRRHOSIS: Abstract

Title:
PERICARDIAL EFFUSION AND LEFT VENTRICULAR DYSFUNCTION IN PATIENTS WITH HEPATIC CIRRHOSIS
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Abstract:

Fluid retention in patients with decompensated hepatic cirrhosis is accompanied by oedema, ascites and hydrothorat Actually it has not been properly studied in Egypt. whether pericardial effusion or left ventricular dysfunction occurs in our patients with such disease or not. This work was particularly dedicated to detect the prevalence of pericardial effusion and to detect the presence of left ventricular dysfunction in patients with decompenSated hepatic cirrhosis using non invasive technique that is echocardiography. This work was conducted on 30 cases of hepatic cirrhosis, classified according to Child's classification into 3 grades, grade A110 patients with compensated hepatic cirrhosis], grade B 110 patients with decompensated hepatic cirrhosis] arid grade C110 patients with decompensated hepatic cirrhosis]. The study included 10 normal controls. We found an incidence of mild to moderate echocardiographically detected pericardial effusion on 3 of 10 patients (30%) of grade B hepatic cirrhosis and, in 4 of 10 patients (40%) of grade C hepatic cirrhosis, so the incidence of pericardial effusion in patients with decompensated hepatic cirrhosis in our study was 7 of 20 patients (3596). None of the patients of grade A hepatic cirrhosis or normal controls had pericardial effusion. This difference in prevalence of pericardial effusion in patients with decompensated hepatic cirrhosis compared to controls proved to be statistically significant. Actually no echocardiographic. laboratory or abdominal sonpgraphic variables could be correlated with the incidence of pericardial effusion except a statistically significant correlation to serum albumin level. As regard to left ventricular functionwefound increased internal diameters of the left ventricle for the patients of the three grades of hepatic cirrhosis. This difference in internal diameters of left ventricle in patients with hepatic cirrhosis compared to controls proved to be statistically significant. In conclusion, pericardial effusion is common in patients with decompensated hepatic cirrhosis and is not accompanied by left ventricular dysfunction.