Publications of Faculty of Medicine:CIRCULATING T-CELL SUBSETS AND IMMUNOGLOBULINS LEVEL IN PATIENTS WITH PULMONARY TUBERCULOSIS: Abstract

Title:
CIRCULATING T-CELL SUBSETS AND IMMUNOGLOBULINS LEVEL IN PATIENTS WITH PULMONARY TUBERCULOSIS
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Abstract:

T- lymphocyte subpopulation (T3. T4 and T8) and serum imrrtunoglobulirts (Ig G. IgA. and Ig M) were estimated in blood of (20) patients with active pulmonary tuberculosis (group I-a), (20) patients With inactive pulmonary tuberculosis (group I-b) and (1()) healthy persons (group II). All subjects were assessed clinically, radiologically, bacteriologically and by tuberculin testing. Active tuberculosis (group I-a) was associated with significant increase in Ig G and Ig M levels, irtsignifcant increase in Ig A level, highly sign(fcant decrease of absolute total lymphocytes. insignificant decrease of T 3%, highly sign(fcant decrease of absolute T3. highly signif cant decrease of T4% and absolute T4, highly signtfcartt increase of T8 and highly signifcartt decrease of T4/T8 ratio. Patients with inactive pulmonary tuberculosis (group 1-b) showed near normal values of serum irnmurtoglobulins (Ig G, M and A), 73, T4, T8 and T4/T8 ratio.