Hepatitis C virus (HCV) infects more than 170 million people worldwide
and around 20% of blood donors are seropositive by ELIZA to HCV Ab in
Egypt. Renal manifestations may be the presenting features of chronic
HCV infection. This work was carried out on 200 patients with chronic
HCV in order to study the relationship between HCV and chronic kidney
disease and to stratify HCV patients according to the degree of albuminuria.
It showed that screening for protenuria in patients with chronic HCV
is necessary due to high prevalence of renal affection in these patients.
Assessment of microalburninuria should be done in these patients as art
early indicator for renal affection. Albumin creatinine ratio (ACR) had a
good reliability as a surrogate measure for routine screening of urine albumin
excretion. Awareness of chronic kidney disease (CKD) stage in patients
with HCV and renal affection help prediction and early management
of renal disease. There was a documented link between
cryoglobulinumic and non-cryoglobulinumic membrano-proliferative glomerulonephritis
and HCV infection. |
