Fasting blood was taken from 15 patients with myocardial
infarction and 15 healthy controls. Membrane lipid peroxidation in
erythrocytes of both groups was examined and compared to
demonstrate its possible relationship with myocardial infarction.
Lipid peroxidation was assessed in fresh erythrocytes by
quantitating malondialdehyde level. Malondialdehyde concentration
was significantly higher (P< 0.05) in patients with myocardial
infarction during the initial 48 hours after an attack. Twelve days
after an attack, serum malondialdehyde decreased but still its level
was higher than controls. It was concluded that lipid peroxidation is
involved in cardiac disease specially myocardial infarction and
accompained by an increase in the production of malondialdehyde |
