The present study included 80 cases with chronic renal failure treated
by maintainance dialysis (50 cases under haemodia/ysis (HD) and 30
cases under peritoneal dialysis PD) to detect the prevalence of hepatitis
virus antibodies among them. Thirty healthy volunteers were also studied
as a control group.
The incidence of anti HCV positive cases was 7696 in HD group. 16. 6%
in PD group and 6.6% in the control group. No specific sex predilection
was found among anti FICV positive cases in any studied group.
There was a significant correlation between number of wilts of blood
transjusion and HCV infection. The mean duration of dialysis was significantly
longer in RD groups .in Anti HCV positive cases as compared to anti
HCV negative cases. By comparing each of anti HCV positive and and
HCV negative cases to either Bilharzial or HBV infection, no statist-WI significant
differences were found. The patterns of liver enzymes abnormality
in the anti HCV positive cases were either a progressively increasing
(15.77% in HD. 40%. in PD and 50%. in the control group) or fluctuating
(15.796. inHD, 20%. in PD. 50%. in the control group).
We might conclude that HCV infection represents a major health problem
among patients with CRY maintained on dialysis particularly those
under haemodialysis. Though blood transfusion represents the major
route of FICV transmission, extended studies of other risk factors such as
insect vectors. schistosomiasis. infected medical or paramedical staff is
mandatory. |